Horizons Clinical Research Center, LLC
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    Over the past few decades the number of people with Type 2 Diabetes has been rising rapidly worldwide.  Although
    there are currently a number of treatments for Type 2 Diabetes there is always a need for new and better
    medications. This research study will evaluate how well the study medication controls type 2 diabetes in conjunction
    with metformin while at the same time evaluating its effectiveness at lowering blood pressure and decreasing weight.

    Study Information:

  • This is a 16 week study with up to 8 clinic visits over the course of the study.
  • The study physician is Cara Dawson, M.D.
  • The principal coordinator of the study is Isabel Arnold RN, BSN, CCRC

    Qualified participants will receive:

  • All clinic visits, lab assessments, medical exams, and study medication at no-cost.
  • Compensation for time and travel.

    To qualify for the study you must:

  • Be at least 18 years old and no older than 75.
  • Have Type 2 Diabetes.
  • Be on a stable regimen of metformin.


    To qualify for the study you must NOT:

  • Be pregnant, nursing or planning to become pregnant if female.
  • Have had two or more emergency room visits in the past 6 months due to hypoglycemia.

    To participate in the study or for more information:

    If you would like to participate in this study please click here and complete the questionnaire.

    If you would like additional information about participating in this study you can also call 303-399-4067.









                                              


    This research study will evaluate how  effectively the new investigational oral medication treats Chronic Idiopathic
    Constipation.

    Study Information:

  • This is a 21 day study with a total of 3 clinic visits.
  • The study physician is Cara Dawson, M.D.
  • The principal coordinator of the study is Isabel Arnold RN, BSN, CCRC

    Qualified participants will receive:

  • All clinic visits, lab assessments, medical exams, and study medication at no-cost.
  • Compensation for time and travel.

    To qualify for the study you must:

  • Be at least 18 years old.
  • Have been diagnosed with chronic idiopathic constipation.
  • If less than 50 you must have documentation of either a flexible sigmoidoscopy or colonoscopy performed within
    past 5 years showing no bowel obstruction or organic disorder of large or small bowel.
  • If 50 or older you must have documentation of either a barium enema with flexible sigmoidoscopy or colonoscopy
    performed within past year showing no bowel obstruction or organic disorder of large or small bowel.

    To qualify for the study you must NOT:

  • Be pregnant or breast-feeding if female.
  • Have been hospitalized for any gastrointestinal or abdominal surgical procedure within the past three months.

    To participate in the study or for more information:

    If you would like to participate in this study please click here and complete the questionnaire.

    If you would like additional information about participating in this study you can also call 303-399-4067.







    The number of people affected by gout has increased over recent decades and it is now estimated that between 3
    and 5 million people in this country suffer from the condition. The purpose of this study is to further research the
    effectiveness of the study medication in treating and preventing gout. The medication in this study has already
    been FDA approved and in fact is the current standard of care for this condition. This is also an open label study
    which means that all participants will receive the study medication.

    Study Information:

  • This is an 27 week study with either 8 or 9 clinic visits.
  • The physician for this study is Dr. Theodore Cooper who is a gynecologist.
  • The principal coordinator of the study is Isabel Arnold RN, BSN, CCRC

    Qualified participants will receive:

  • All clinic visits, lab assessments, medical exams, and study medication at no-cost.
  • Compensation for time and travel.

    To qualify for the study you must:

  • Be at least 18 and no older than 85.
  • Have been diagnosed with gout.
  • Have had at least two gout flair ups in the past year.

    To qualify for the study you must NOT:

  • Have uncontrolled hypertension.
  • Must not be pregnant, nursing or planning to become pregnant during the course of the study.

    To participate in the study or for more information:

    If you would like to participate in this study please click here and complete the questionnaire.

    If you would like additional information about participating in this study you can also call 303-399-4067.











    Osteoarthritis of the knee is believed to affect at least 30% of the population over the age of 65. It is a chronically
    progressive disease with signs and symptoms of pain, stiffness, restricted motion and the sounds or sensation of
    grating, crackling or popping. As the disease progresses mobility can become severely restricted and eventually
    lead to joint replacement.

    There is no cure for this disease and current treatments focus on relieving pain and maintaining joint movement.
    Oral prescription and over-the-counter anti-inflammatory pain relievers are most commonly used as treatments;
    however, long-term use of these have substantial risk of side effects.

    At present there is only one topical pain reliever that is FDA approved to treat Osteoarthritis and it has grown in
    popularity because of its proven effectiveness and safety record. This study is testing the comparative
    effectiveness of a generic version of this medication.

    Study Information:

  • This is a 4 week study with 4 clinic visits.
  • The physician for this study is Dr. Cara Dawson.
  • The principal coordinator of the study is Isabel Arnold RN, BSN, CCRC

    Qualified participants will receive:

  • All clinic visits, lab assessments, medical exams, and study medication at no-cost.
  • Compensation for time and travel.

    To qualify for the study you must:

  • Be at least 35 years old.
  • Experience pain associated with osteoarthritis in one or both knees.

    To qualify for the study you must NOT:

  • Must not be pregnant, nursing or planning to become pregnant during the course of the study.

    To participate in the study or for more information:

    If you would like to participate in this study please click here and complete the questionnaire.

    If you would like additional information about participating in this study you can also call 303-399-4067.







    Do you have high blood pressure, also known as hypertension? 76 million American adults struggle with
    hypertension. It may be difficult to control, but without adequate treatment high blood pressure can cause health
    complications. Researchers are actively pursuing new treatments to control hypertension. This important clinical
    research study is evaluating an investigational combination of FDA-approved oral medicines.

    Study Information:

  • This is up to a 16 week study with up to a total of 13 clinic visits.
  • The physician for this study is Dr. Cara Dawson.
  • The principal coordinator of the study is Isabel Arnold RN, BSN, CCRC

    Qualified participants will receive:

  • All clinic visits, lab assessments, medical exams, and study medication at no-cost.
  • Compensation for time and travel.

    To qualify for the study you must:

  • Be at least 18 years old.
  • Must have been diagnosed with hypertension.

    To qualify for the study you must NOT:

  • Have any kind of heart condition.
  • Must not be pregnant, nursing or planning to become pregnant during the course of the study.
  • Have type 1 diabetes or uncontrolled type 2 diabetes.

    To participate in the study or for more information:

    If you would like to participate in this study please click here and complete the questionnaire.

    If you would like additional information about participating in this study you can also call 303-399-4067.





                                            
    This research study will evaluate how  effectively the new investigational oral medication treats opioid-induced
    constipation.

    Study Information:

  • This is a 12 week study with a total of 7 clinic visits.
  • The study physician is Cara Dawson, M.D.
  • The principal coordinator of the study is Isabel Arnold RN, BSN, CCRC

    Qualified participants will receive:

  • All clinic visits, lab assessments, medical exams, and study medication at no-cost.
  • Compensation for time and travel.

    To qualify for the study you must:

  • Be at least 18 years old.
  • Have non-malignant chronic pain experiencing opioid-induced constipation. (Less than 3 spontaneous bowel
    movements per week)

    To qualify for the study you must NOT:

  • Be pregnant or breast-feeding if female.

    To participate in the study or for more information:

    If you would like to participate in this study please click here and complete the questionnaire.

    If you would like additional information about participating in this study you can also call 303-399-4067.








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Below are the clinical research studies in internal medicine that are currently enrolling patients.

Type 2 Diabetes
Chronic Idiopathic Constipation
Gout
Osteoarthritis of the Knee
Hypertension
Opioid-Induced Constipation

Enrolling Internal Medicine Studies

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